ALLERGIES AND THE THREE OPTIONS 

This is not our allergy page- just a very basic starter page before it is launched to understand our 3 options. 

All our page and information is copy righted .

We have three options  to assist with allergies .

1) laboratory tested kittens  THE GOLD STANDARD

2) Home sittings THE SILVER STANDARD 

3) Fur samples THE BRONZE STANDARD  

Silver and Bronze services are offered to everyone even if you are not adopting from us.

If you would like to adopt from us we require  you order  fur samples as a minimum .

We do recommend a sitting and backed up with fur samples or for the gold standard of security laboratory tested kitten .

We require fur samples to be ordered as a minimum to protect each party and to minimise  the return the kittens . It is a good tool at assessing your own allergies.

We understand home sittings due to covid 19 isn’t always possible, but we are willing to hold sittings when restrictions ease. 

We have 15 years experience with allergies with fur samples and sittings , and the  First UK cattery to start offering fur samples in the UK in Siberians .

In the UK to date we are the First and only UK cattery  to be testing  the FELD1 and FELD4 with such extensive studies and data to back up all our claims .

We have two years of kitten placements for level 3  4 to 5 and 100% success rate to date.

We are proud to  continue to help families  and owners to have a special companion in their life .

Within  our studies we have worked with all levels  and extensively with severe and chronic asthma sufferers and  also children with excellent success .

Are Siberians really Hypoallergenic ?

We decided that over two years ago to find out the truth just like you may of …. we had heard so many stories in  our 15 years breeding,  different ways and information. 

Every  breeder has  different take on things and contradictions … So we asked ourselves  what’s the truth  here when no one had any proof or studies themselves or done any testing in the UK ?  

We have found  from our own studies  that most  if not all information  out there is incorrect to an extent  or with falsehoods and or with  misleading information at best .

 All our kings and queens have been FELD4 tested and our young females have been FELD1 Tested and we have started to hold back level 4-5 queens and kings for our own breeding program.

We offer a FELD1 tested Siberian kitten  which can leave at 14 weeks and we can offer the FELD4 fur    testing alongside   the FELD1 .

What causes allergies? 

There are many myths and misconceptions related to cat allergens and many people who suffer from cat allergies do not fully understand the actual cause of their allergy.

What is an allergic reaction 

Pathophysiology

immunoglobulin E (IgE)  meaning  is antibodies produced by the immune system. If you have an allergy, your immune system overreacts to an allergen by producing antibodies called Immunoglobulin E (IgE). These antibodies travel to cells that release chemicals, causing an allergic reaction.

As the allergen enters through the nose or mouth, antigen cells analyze the allergen and present antigenic peptides to helper T cells The helper T cells acquire a type 2 phenotype (Th2) and produce IgE due to the presence of specific cytokines. If Th2 is expressed too much, the symptoms of cat allergies appear. Inhaled cat allergens will activate mast cells, causing coughing, increased mucus production, and airway constriction.

Cat allergens have significant allergenicity. They are also numerous and cat allergen extracts are therefore a multi-allergenic source.  10 allergens have been identified in studies of extracts from fur, saliva, serum and urine

anti-Fel d 1 specific IgE is found in the serum of more than 80–98% of patients allergic to cats.

Eight cat allergens have been registered to date (Fel d 1 to Feld d 8)

The most important cat allergen in disease pathogenesis is, unlike in other mammals, a secretoglobin, called Fel d 1.

Fel d 1 is easily airborne and remains in the indoor environment for up to 6 months after the cat is removed .

FELD1 is responsible for over 80% of reactions .

What is Feld1?

fel d 1 is a secretoglobin protein that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes.Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens. The function of the protein for cats is unknown, but it causes an IgG or IgE reaction in sensitive humans (either as an allergic or asthmatic response).

Kittens produce less Fel d 1 than adult cats. Female cats produce a lower level of Fel d 1 than (unneutered) males,while neutered males produce levels similar to those of females. Both intact and spayed females produce similar levels.

Although females and neutered males produce Fel d 1 in lower levels, they still produce enough to cause allergic symptoms in sensitive individuals.

We have designed  specialist testing to determine the real level of a kittens and cats hypoallergenic level regardless of ageing and sex.

WHY ARE SIBERIANS THE PERFECT BREED FOR ALLERGIES.

Siberian breed, native to the Siberian region for which the breed is named, have been shown to have genetic variants that result in a lower production of Fel d 1.

Siberians compared to all other cat breeds have up to a 50% lower allergen level  which is a big plus point for Siberians and assists  with higher success stories among suffers. 

The Siberian Cat produces a lower level   of FEL D1, due to a protein sequence missing from their DNA. Only pure-bred  pedigree Siberian cats will have this genetic advantage. 

Meaning the hypoallergenic cat DOES exist, it’s just finding that needle in the haystack.

allergies to cats are one of the most common allergies among individuals. Among the eight known cat allergens, the most prominent allergen is secretoglobin Fel d 1, and it is produced in the anal glands, salivary glands, and, mainly, in sebaceous glands of cats, Allergic symptoms associated with cats include coughing, wheezing, chest tightening, itching, nasal congestion, rash, watering eyes, sneezing, chapped lips, and similar symptoms. In worst-case scenarios, allergies to cats can develop into more life-threatening conditions such as rhinitis and mild to severe forms of asthma. Despite these symptoms, there are many types of solutions to mitigate the allergic effects of cats, including medications, vaccines, and home remedies. Hypoallergenic cats are another solution for individuals who want pets without the allergic consequences. Furthermore, prospective pet owners can reduce allergic reactions by selecting cats  such as the siberian  which are associated with a lower production of allergens.

The secretion and production  of the Fel d1 allergen is often  controlled by stress and hormones and changes to hormones. 

ARE SIBERIANS REALLY HYPOALLERGENIC 

YES 

THE HYPOALLERGENIC CAT DOES EXIST.

HOWEVER EVERY KITTEN AND CAT HAS A DIFFERENT LEVEL, 

Simplified version  some will be hypoallergenic yes , however with out testing it is a lottery to know which is low level or high level and how hypoallergenic a cat or kitten truly is to suit your allergie level. 

Siberians compared to all other cat breeds have up to a 50% lower allergen level  which is a big plus point for Siberians and assists  with higher success stories among suffers. 

The Siberian Cat produces a lower level   of FEL D1, due to a protein sequence missing from their DNA. Only pure-bred  pedigree Siberian cats will have this genetic advantage. 

The domestic cat is  the most common source for the most inhiladed allergens and affects up to 20% of the population and  is often associated with asthma.

FELD1 is the main coarse of all reactions up to 80% of reactions.

FELD2 is responsible for up to 15% of reactions 

Serum albumin, often referred to simply as blood albumin, is an albumin found in vertebrate blood. Human serum albumin is encoded by the ALB gene. Other mammalian forms, such as bovine serum albumin, are chemically similar. 

Many people if they have additional  allergies to rabbits, dogs or horses  certain meats such as pork meat could be more sensitive to Siberians and still be  triggered by feld1 .  there are Over 14  additional substances that can cause allergic reactions have been identified in all mammals, 

FELD4 up to 20%  

 Fel d 4 is a lipocalin allergen produced by the cat, which binds IgE at relatively high frequency in cat-sensitive individuals. The allergen provides not only a means for investigating differences in the immune response to lipocalin allergens from that found for other mammalian species but also an important reagent for the diagnosis of cat allergy.

Fel d 4 and Fel d 7

Fel d 4 and Fel d 7 are cat lipocalins. Fel d 4 and Fel d 7 are one of the most common cat allergens after Fel d 1. Fel d 4 is produced in the submandibular salivary glands and secreted into the saliva of cats, via which it is deposited on to cat dander during grooming, and is associated with atopic dermatitis in children with cat allergies.

INCORRECT WAYS TO ASSES ALLERGIES 

 In the UK and Europe  there are many  incorrect ways of assessing people’s allergies  and strong statements out there from breeders saying  for example  a sitting  with a  neutered retired male  is a reliable and effective  way to assess one’s allergies.

This is highly  incorrect  and pointless exercise to do  and  will still be  like a lottery  when you take your kitten or cats home.

Many breeders only work with mild allergies only, to why they will have only good success stories  and make strong statements  that sittings have always worked this way…  sometimes discrimination  does happen by who they allow on there lists.

As we said  as a whole we have a very good success rate with mild only and would have a near enough 100% success rate just working with this level only.

The  reality is a lot of people have more than mild allergies .

There is a big difference  between mild to  medium to severe allergies which we work with to try and help everyone with allergies not just the easy cases. 

We know of stories of large deposits been lost on return of the kittens which  could be avoided with better knowledge and understanding off allergies .

Alot of breeders choose not to work with allergies as it is very complex and this is more than ok.

Above is  just one example we do  not recommended to do as it has no reliability or credibility to do and could result in  a false sense of security if you are not allergic when in fact you very well could be.

A neutered male can have a  lower FELD1 ( in depth info to come on our allergies page) and the male  could also just be a low allergen Siberian.

 It has no relevance on the kitten you are going to get  and you could be testing your allergies with a low allergen level Siberian .. and worse it is not a parent to have any genetic influence over if any litters of kittens . 

So this is the number one wrong way to asses allergies among with other examples.

We have had 15 years of  good success with fur samples and home sittings and generally all  mild suffers are completely  fine with  all Siberians which is excellent.

SIBERIANS ARE THE NUMBER ONE BREED FOR ALLERGIES .

 For security we  just double check for caution with fur samples or sittings for the owners benefit and the kittens.  . 

THIS IS WHY FOR US TO ADOPT TO YOU WE REQUIRE YOU TRY AT MINIMUM FUR SAMPLES.